SuperFreq: Integrated mutation detection and clonal tracking in cancer.

Analysing multiple cancer samples from an individual patient can provide insight into the way the disease evolves. Monitoring the expansion and contraction of distinct clones helps to reveal the mutations that initiate the disease and those that drive progression. Existing approaches for clonal trac...

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Bibliographic Details
Main Authors: Christoffer Flensburg, Tobias Sargeant, Alicia Oshlack, Ian J Majewski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-02-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007603