CCR2/CCL2-mediated inflammation protects photoreceptor cells from amyloid-β-induced apoptosis
Age-related macular degeneration is characterized by the formation of drusen containing amyloid-β (Aβ) and the degeneration of photoreceptors. To explore the largely unknown role of Aβ in the retina, we investigated the effects on photoreceptors of the oligomeric form of Aβ(1–42). Subretinal injecti...
Main Authors: | Julien Bruban, Agathe Maoui, Naïma Chalour, Na An, Laurent Jonet, Charles Feumi, Jacques Tréton, Florian Sennlaub, Francine Behar-Cohen, Frédéric Mascarelli, Virginie Dinet |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2011-04-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996111000052 |
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