A Prenylated Xanthone, Cudratricusxanthone A, Isolated from Cudrania tricuspidata Inhibits Lipopolysaccharide-Induced Neuroinflammation through Inhibition of NF-κB and p38 MAPK Pathways in BV2 Microglia

A Prenylated Xanthone, Cudratricusxanthone A, Isolated from Cudrania tricuspidata Inhibits Lipopolysaccharide-Induced Neuroinflammation through Inhibition of NF-κB and p38 MAPK Pathways in BV2 Microglia

Cudrania tricuspidata Bureau (Moraceae) is an important source of traditional Korean and Chinese medicines used to treat neuritis and inflammation. Cudratricusxanthone A (1), a prenylated xanthone, isolated from C. tricuspidata, has a variety of biological and therapeutic activities. The goal of thi...

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Bibliographic Details
Main Authors: Chi-Su Yoon, Dong-Cheol Kim, Tran Hong Quang, Jungwon Seo, Dae Gill Kang, Ho Sub Lee, Hyuncheol Oh, Youn-Chul Kim
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Molecules
Subjects:
Cudrania tricuspidata
cudratricusxanthone A
microglia
neuroinflammation
nuclear factor-kappa B
mitogen-activated protein kinase
Online Access:http://www.mdpi.com/1420-3049/21/9/1240

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http://www.mdpi.com/1420-3049/21/9/1240

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