Detection of cell-free microbial DNA using a contaminant-controlled analysis framework

Detection of cell-free microbial DNA using a contaminant-controlled analysis framework

Abstract Background The human microbiome plays an important role in cancer. Accumulating evidence indicates that commensal microbiome-derived DNA may be represented in minute quantities in the cell-free DNA of human blood and could possibly be harnessed as a new cancer biomarker. However, there has...

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Bibliographic Details
Main Authors: Enrique Zozaya-Valdés, Stephen Q. Wong, Jeanette Raleigh, Athena Hatzimihalis, Sarah Ftouni, Anthony T. Papenfuss, Shahneen Sandhu, Mark A. Dawson, Sarah-Jane Dawson
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Genome Biology
Subjects:
Cell-free microbial DNA
Plasma
Microbiome
Cancer
Contamination
16S rRNA gene
Online Access:https://doi.org/10.1186/s13059-021-02401-3

Internet

https://doi.org/10.1186/s13059-021-02401-3

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