Abnormal activation of insulin-like growth factor-I receptor in hepatocellular carcinoma and potential of IGF-IR targeted therapy
Abnormal activation of the insulin-like growth factor-I receptor (IGF-IR) occurs during malignant transformation of hepatocytes and during hepatocarcinogenesis. IGF-IR overexpression has been proposed as a diagnostic biomarker for early-stage hepatocellular carcinoma (HCC) as well as a novel target...
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Format: | Article |
Language: | zho |
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Editorial Department of Journal of Clinical Hepatology
2013-06-01
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Series: | Linchuang Gandanbing Zazhi |
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Online Access: | http://www.lcgdbzz.org/qk_content.asp?id=5384&ClassID=5693339 |