Abnormal activation of insulin-like growth factor-I receptor in hepatocellular carcinoma and potential of IGF-IR targeted therapy

Abnormal activation of the insulin-like growth factor-I receptor (IGF-IR) occurs during malignant transformation of hepatocytes and during hepatocarcinogenesis. IGF-IR overexpression has been proposed as a diagnostic biomarker for early-stage hepatocellular carcinoma (HCC) as well as a novel target...

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Bibliographic Details
Main Author: YAN Xiaodi
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2013-06-01
Series:Linchuang Gandanbing Zazhi
Subjects:
Online Access:http://www.lcgdbzz.org/qk_content.asp?id=5384&ClassID=5693339