Identifying States of Collateral Sensitivity during the Evolution of Therapeutic Resistance in Ewing's Sarcoma

Identifying States of Collateral Sensitivity during the Evolution of Therapeutic Resistance in Ewing's Sarcoma

Summary: Advances in the treatment of Ewing's sarcoma (EWS) are desperately needed, particularly in the case of metastatic disease. A deeper understanding of collateral sensitivity, where the evolution of therapeutic resistance to one drug aligns with sensitivity to another drug, may improve ou...

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Bibliographic Details
Main Authors: Jessica A. Scarborough, Erin McClure, Peter Anderson, Andrew Dhawan, Arda Durmaz, Stephen L. Lessnick, Masahiro Hitomi, Jacob G. Scott
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:iScience
Subjects:
Biological Sciences
Evolutionary Biology
Cancer Systems Biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220304806

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http://www.sciencedirect.com/science/article/pii/S2589004220304806

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