Transplantation of Neural Crest-Like Cells Derived from Induced Pluripotent Stem Cells Improves Diabetic Polyneuropathy in Mice

Impaired vascularity and nerve degeneration are the most important pathophysiological abnormalities of diabetic polyneuropathy (DPN). Therefore, regeneration of both the vascular and nervous systems is required for the treatment of DPN. The neural crest (NC) is a transient embryonic structure in ver...

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Bibliographic Details
Main Authors: Tetsuji Okawa, Hideki Kamiya, Tatsuhito Himeno, Jiro Kato, Yusuke Seino, Atsushi Fujiya, Masaki Kondo, Shin Tsunekawa, Keiko Naruse, Yoji Hamada, Nobuaki Ozaki, Zhao Cheng, Tetsutaro Kito, Hirohiko Suzuki, Sachiko Ito, Yutaka Oiso, Jiro Nakamura, Ken-Ichi Isobe
Format: Article
Language:English
Published: SAGE Publishing 2013-10-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X657710