13-Methylberberine improves endothelial dysfunction by inhibiting NLRP3 inflammasome activation via autophagy induction in human umbilical vein endothelial cells

13-Methylberberine improves endothelial dysfunction by inhibiting NLRP3 inflammasome activation via autophagy induction in human umbilical vein endothelial cells

Abstract Background Atherosclerosis, the underlying cause of the majority of cardiovascular diseases, is a lipid-driven, inflammatory disease of the large arteries. Atherosclerotic cardiovascular disease (ASCVD) threatens human lives due to high morbidity and mortality. Many studies have demonstrate...

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Bibliographic Details
Main Authors: Zhihua Peng, Hong Zhan, Yijia Shao, Yan Xiong, Lijin Zeng, Cong Zhang, Zhihao Liu, Zhenhua Huang, Huanxing Su, Zhen Yang
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Chinese Medicine
Subjects:
13-Methylberberine
Atherosclerosis
Anti-inflammatory
Autophagy inducer
NLRP3 inflammasome
Online Access:https://doi.org/10.1186/s13020-020-0286-1

Internet

https://doi.org/10.1186/s13020-020-0286-1

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