Small molecules targeting coxsackievirus A16 capsid inactivate viral particles and prevent viral binding

Abstract Coxsackievirus A16 (CVA16) is an etiologic agent of hand, foot, and mouth disease (HFMD) that affects young children, and although typically self-limited, severe complications, and fatal cases have been reported. Due to the lack of specific medication and vaccines against CVA16, there is cu...

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Bibliographic Details
Main Authors: Chien-Ju Lin, Ching-Hsuan Liu, Jonathan Y. Wang, Chun-Ching Lin, Yi-Fang Li, Christopher D. Richardson, Liang-Tzung Lin
Format: Article
Language:English
Published: Taylor & Francis Group 2018-09-01
Series:Emerging Microbes and Infections
Online Access:http://link.springer.com/article/10.1038/s41426-018-0165-3