Estimating Detection Limits in Chromatography from Calibration Data: Ordinary Least Squares Regression vs. Weighted Least Squares
It is necessary to determine the limit of detection when validating any analytical method. For methods with a linear response, a simple and low labor-consuming procedure is to use the linear regression parameters obtained in the calibration to estimate the blank standard deviation from the residual...
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Format: | Article |
Language: | English |
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MDPI AG
2018-10-01
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Series: | Separations |
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Online Access: | http://www.mdpi.com/2297-8739/5/4/49 |