Sitagliptin Mitigates Total Body Irradiation-Induced Hematopoietic Injury in Mice

Sitagliptin, an inhibitor of the dipeptidyl peptidase IV (DPP4), has been implicated in the regulation of type 2 diabetes. However, the role and mechanism of sitagliptin administration in total body irradiation (TBI)- induced hematopoietic cells injury are unclear. In this study, we demonstrated tha...

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Bibliographic Details
Main Authors: Meifang Wang, Yinping Dong, Jing Wu, Hongyan Li, Junling Zhang, Lu Lu, Yuanyang Zhang, Zewei Zhou, Saijun Fan, Deguan Li, Aimin Meng
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/8308616