Developing Fast Fluorescent Protein Voltage Sensors by Optimizing FRET Interactions.

FRET (Förster Resonance Energy Transfer)-based protein voltage sensors can be useful for monitoring neuronal activity in vivo because the ratio of signals between the donor and acceptor pair reduces common sources of noise such as heart beat artifacts. We improved the performance of FRET based genet...

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Bibliographic Details
Main Authors: Uhna Sung, Masoud Sepehri-Rad, Hong Hua Piao, Lei Jin, Thomas Hughes, Lawrence B Cohen, Bradley J Baker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4654489?pdf=render