Significance of NPM1 Gene Mutations in AML

The aim of this literature review is to examine the significance of the nucleophosmin 1 (<i>NPM1</i>) gene in acute myeloid leukaemia (AML). This will include analysis of the structure and normal cellular function of NPM1, the type of mutations commonly witnessed in <i>NPM1</i&g...

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Bibliographic Details
Main Authors: Andrew Hindley, Mark Alexander Catherwood, Mary Frances McMullin, Ken I. Mills
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
AML
Online Access:https://www.mdpi.com/1422-0067/22/18/10040