Multi-Domain Touchscreen-Based Cognitive Assessment of C57BL/6J Female Mice Shows Whole-Body Exposure to 56Fe Particle Space Radiation in Maturity Improves Discrimination Learning Yet Impairs Stimulus-Response Rule-Based Habit Learning
Astronauts during interplanetary missions will be exposed to galactic cosmic radiation, including charged particles like 56Fe. Most preclinical studies with mature, “astronaut-aged” rodents suggest space radiation diminishes performance in classical hippocampal- and prefrontal cortex-dependent tasks...
Main Authors: | Ivan Soler, Sanghee Yun, Ryan P. Reynolds, Cody W. Whoolery, Fionya H. Tran, Priya L. Kumar, Yuying Rong, Matthew J. DeSalle, Adam D. Gibson, Ann M. Stowe, Frederico C. Kiffer, Amelia J. Eisch |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-10-01
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Series: | Frontiers in Behavioral Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnbeh.2021.722780/full |
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