Metabolome analysis reveals a role for glyceraldehyde 3-phosphate dehydrogenase in the inhibition of C. thermocellum by ethanol

Metabolome analysis reveals a role for glyceraldehyde 3-phosphate dehydrogenase in the inhibition of C. thermocellum by ethanol

Abstract Background Clostridium thermocellum is a promising microorganism for conversion of cellulosic biomass to biofuel, without added enzymes; however, the low ethanol titer produced by strains developed thus far is an obstacle to industrial application. Results Here, we analyzed changes in the r...

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Bibliographic Details
Main Authors: Liang Tian, Skyler J. Perot, David Stevenson, Tyler Jacobson, Anthony A. Lanahan, Daniel Amador-Noguez, Daniel G. Olson, Lee R. Lynd
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Biotechnology for Biofuels
Subjects:
Consolidated bioprocessing
Clostridium thermocellum
Ethanol tolerance
Metabolomic analysis
Online Access:http://link.springer.com/article/10.1186/s13068-017-0961-3

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http://link.springer.com/article/10.1186/s13068-017-0961-3

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