Impact of expansion and redifferentiation under hypothermia on chondrogenic capacity of cultured human septal chondrocytes

A critical limitation in the cultivation of cartilage for tissue engineering is the dedifferentiation in chondrocytes, mainly during in vitro amplification. Despite many previous studies investigating the influence of various conditions, no data exist concerning the effects of hypothermia. Our aim h...

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Bibliographic Details
Main Authors: Achim von Bomhard, Joseph Faust, Alexander F Elsaesser, Silke Schwarz, Katharina Pippich, Nicole Rotter
Format: Article
Language:English
Published: SAGE Publishing 2017-10-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/2041731417732655