Clinical Evaluation of M30 and M65 ELISA Cell Death Assays as Circulating Biomarkers in a Drug-Sensitive Tumor, Testicular Cancer

Circulating full-length and caspase-cleaved cytokeratin 18 (CK18) are considered biomarkers of chemotherapy-induced cell death measured using a combination of the M30 and M65 ELISAs. M30 measures caspase-cleaved CK18 produced during apoptosis and M65 measures the levels of both caspase-cleaved and...

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Main Authors: Esther C. de Haas, Alessandra di Pietro, Kathryn L. Simpson, Coby Meijer, Albert J.H. Suurmeijer, Lee J. Lancashire, J. Cummings, Steven de Jong, Elisabeth G.E. de Vries, Caroline Dive, Jourik A. Gietema
Format: Article
Language:English
Published: Elsevier 2008-10-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608800942