Role of Nitric Oxide and Metallothionein in Cytotoxic Activity of Cadmium in Caco-2 Cells

Role of Nitric Oxide and Metallothionein in Cytotoxic Activity of Cadmium in Caco-2 Cells

Cadmium (Cd) induces carcinogenicity and cytotoxicity through a variety of mechanisms. Metallothioneins (MTs) play critical roles in metal detoxification and radical scavenging. Here we evaluated the possible involvement of NO and MT in Cd-induced toxicity and resistance development. By utilizing C...

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Bibliographic Details
Main Authors: Farnaz Malekmarzban, Mohammad Seyedabad, Mohammad Hossein Ghahreman, Shima Aliebrahimi, Peiman Habibollahi, Shohreh Tavajohi, Seyed Nasser Ostad
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2018-05-01
Series:Acta Medica Iranica
Subjects:
Heavy metal
Detoxification
Free radical
iNOS
Colon carcinoma
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/6118

Internet

https://acta.tums.ac.ir/index.php/acta/article/view/6118

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