DHA induces mitochondria-mediated 3T3-L1 adipocyte apoptosis by down-regulation of Akt and ERK

DHA induces mitochondria-mediated 3T3-L1 adipocyte apoptosis by down-regulation of Akt and ERK

Docosahexaenoic acid (DHA) possesses various bioactivities. However, the effects of DHA on adipocyte homeostasis remain unclear. Here the effects of DHA (0, 50, 100, 150 µM) on the apoptosis of mature 3T3-L1 adipocytes was investigated in order to elucidate potential mechanisms. It was shown that DH...

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Bibliographic Details
Main Authors: An-Shi Wang, Chen-Wei Xu, Hong-Yan Xie, An-Jun Yao, Ying-Zhuo Shen, Jing-Jing Wan, Hui-Qing Zhang, Jian-Fei Fu, Zhong-Ming Chen, Zu-Quan Zou, Duo Li, Xiao-Hong Zhang
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Journal of Functional Foods
Subjects:
Docosahexaenoic acid
3T3-L1 adipocytes
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464616000025

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http://www.sciencedirect.com/science/article/pii/S1756464616000025

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