Use of broad-spectrum antibiotics impacts outcome in patients treated with immune checkpoint inhibitors

Use of broad-spectrum antibiotics impacts outcome in patients treated with immune checkpoint inhibitors

We carried out a retrospective cohort study on patients with advanced cancer treated with immune checkpoint inhibitors (ICIs) to determine whether antibiotics affect treatment outcome. Sixty consecutive patients were identified, and 17 received systemic antibiotics within 2 weeks before and/or after...

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Bibliographic Details
Main Authors: Jibran Ahmed, Arun Kumar, Kaushal Parikh, Asad Anwar, Bettina M Knoll, Carmelo Puccio, Hoo Chun, Michael Fanucchi, Seah H Lim
Format: Article
Language:English
Published: Taylor & Francis Group 2018-11-01
Series:OncoImmunology
Subjects:
immune checkpoint inhibitors
broad-spectrum antibiotics
narrow-spectrum antibiotics
progression-free survival
response rate
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1507670

Internet

http://dx.doi.org/10.1080/2162402X.2018.1507670

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