GRAY AND WHITE MATTER DEMYELINATION AND REMYELINATION DETECTED WITH MULTIMODAL QUANTITATIVE MRI ANALYSIS AT 11.7T IN A CHRONIC MOUSE MODEL OF MULTIPLE SCLEROSIS

GRAY AND WHITE MATTER DEMYELINATION AND REMYELINATION DETECTED WITH MULTIMODAL QUANTITATIVE MRI ANALYSIS AT 11.7T IN A CHRONIC MOUSE MODEL OF MULTIPLE SCLEROSIS

Myelin is a component of the nervous system that is disrupted in multiple sclerosis, resulting in neuro-axonal degeneration. The longitudinal effect of chronic cuprizone-induced demyelination was investigated in the cerebral gray and white matter of treated mice and the spontaneous remyelination upo...

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Bibliographic Details
Main Authors: Alexandra Petiet, Marie-Stéphane Aigrot, Bruno Stankoff
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Neuroscience
Subjects:
Cuprizone
Diffusion
Multiple Sclerosis
demyelination
remyelination
T2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00491/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00491/full

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