GNAS mutations identify a set of right-sided, RAS mutant, villous colon cancers.

The purpose of this study is to determine the genetic frequency of GNAS activating mutations in colorectal cancer and the corresponding pathology of GNAS mutant tumors. Oncogenic mutations in GNAS have been described in a number of neoplasms including those of the pituitary, kidney, pancreas, and, m...

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Bibliographic Details
Main Authors: Ryan E Fecteau, James Lutterbaugh, Sanford D Markowitz, Joseph Willis, Kishore Guda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3907576?pdf=render