Antiamoebic Activities of Indolocarbazole Metabolites Isolated from <i>Streptomyces sanyensis</i> Cultures

Antiamoebic Activities of Indolocarbazole Metabolites Isolated from <i>Streptomyces sanyensis</i> Cultures

Indolocarbazoles are a family of natural alkaloids characterized by their potent protein kinase and topoisomerase I inhibitory activity. Among them, staurosporine (<b>1</b>) has exhibited promising inhibitory activity against parasites. Based on new insights on the activity and mechanism...

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Bibliographic Details
Main Authors: Luis Cartuche, María Reyes-Batlle, Ines Sifaoui, Iñigo Arberas-Jiménez, José E. Piñero, José J. Fernández, Jacob Lorenzo-Morales, Ana R. Díaz-Marrero
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Marine Drugs
Subjects:
indolocarbazole
staurosporine
<i>streptomyces sanyensis</i>
antiparasitic activities
<i>acanthamoeba</i>
Online Access:https://www.mdpi.com/1660-3397/17/10/588

Internet

https://www.mdpi.com/1660-3397/17/10/588

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