Pro-opiomelanocortin (POMC) neuron translatome signatures underlying obesogenic gestational malprogramming in mice

Pro-opiomelanocortin (POMC) neuron translatome signatures underlying obesogenic gestational malprogramming in mice

Objective: Maternal unbalanced nutritional habits during embryonic development and perinatal stages perturb hypothalamic neuronal programming of the offspring, thus increasing obesity-associated diabetes risk. However, the underlying molecular mechanisms remain largely unknown. In this study we soug...

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Bibliographic Details
Main Authors: Roberta Haddad-Tóvolli, Jordi Altirriba, Arnaud Obri, Elena Eyre Sánchez, Iñigo Chivite, Maria Milà-Guasch, Sara Ramírez, Alicia G. Gómez-Valadés, Macarena Pozo, Jasmine Burguet, Licio A. Velloso, Marc Claret
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Metabolism
Subjects:
POMC neuron
RiboTag
Neuronal programming
Obesity
Translatome
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820300351

Internet

http://www.sciencedirect.com/science/article/pii/S2212877820300351

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