Phase 2 Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors

Phase 2 Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors

IntroductionTreatment of recurrent primary pediatric brain tumors remains a major challenge, with most children succumbing to their disease. We conducted a prospective phase 2 study investigating the safety and efficacy of pomalidomide (POM) in children and young adults with recurrent and progressiv...

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Bibliographic Details
Main Authors: Jason Fangusaro, Maria Giuseppina Cefalo, Maria Luisa Garré, Lynley V. Marshall, Maura Massimino, Bouchra Benettaib, Noha Biserna, Jennifer Poon, Jackie Quan, Erin Conlin, John Lewandowski, Mathew Simcock, Neelum Jeste, Darren R. Hargrave, François Doz, Katherine E. Warren
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
diffuse intrinsic pontine glioma
ependymoma
high-grade glioma
medulloblastoma
pomalidomide
progressive or recurrent disease
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.660892/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.660892/full

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