JNK2 regulates vascular remodeling in pulmonary hypertension

Pulmonary arterial (PA) wall modifications are key pathological features of pulmonary hypertension (PH). Although such abnormalities correlate with heightened phosphorylation of c-Jun N-terminal kinases 1/2 (JNK1/2) in a rat model of PH, the contribution of specific JNK isoforms to the pathophysiolo...

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Bibliographic Details
Main Authors: Mita Das, W. Michael Zawada, James West, Kurt R. Stenmark
Format: Article
Language:English
Published: SAGE Publishing 2018-07-01
Series:Pulmonary Circulation
Online Access:https://doi.org/10.1177/2045894018778156