Annotation error in public databases: misannotation of molecular function in enzyme superfamilies.

Due to the rapid release of new data from genome sequencing projects, the majority of protein sequences in public databases have not been experimentally characterized; rather, sequences are annotated using computational analysis. The level of misannotation and the types of misannotation in large pub...

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Bibliographic Details
Main Authors: Alexandra M Schnoes, Shoshana D Brown, Igor Dodevski, Patricia C Babbitt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20011109/?tool=EBI