ONGOING OXIDATIVE STRESS CAUSES SUBCLINICAL NEURONAL DYSFUNCTION IN THE RECOVERY PHASE OF EAE

ONGOING OXIDATIVE STRESS CAUSES SUBCLINICAL NEURONAL DYSFUNCTION IN THE RECOVERY PHASE OF EAE

Most multiple sclerosis patients develop over time a secondary progressive disease course, characterized histologically by axonal loss and atrophy. In early phases of the disease, focal inflammatory demyelination leads to functional impairment, but the mechanism of chronic progression in multiple sc...

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Bibliographic Details
Main Authors: Helena eRadbruch, Daniel eBremer, Robert eGuenther, Zoltan eCseresnyes, Randall eLindquist, Anja E Hauser, Raluca eNiesner
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Immunology
Subjects:
Calcium
NOX
EAE/MS
intravital imaging
FLIM-FRET
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00092/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00092/full

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