N-acetylcysteine inhibits bacterial lipopeptide-mediated neutrophil transmigration through the choroid plexus in the developing brain

N-acetylcysteine inhibits bacterial lipopeptide-mediated neutrophil transmigration through the choroid plexus in the developing brain

Abstract The etiology of neurological impairments associated with prematurity and other perinatal complications often involves an infectious or pro-inflammatory component. The use of antioxidant molecules have proved useful to protect the neonatal brain from injury. The choroid plexuses-CSF system s...

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Bibliographic Details
Main Authors: Amin Mottahedin, Sandrine Blondel, Joakim Ek, Anna-Lena Leverin, Pernilla Svedin, Henrik Hagberg, Carina Mallard, Jean-Francois Ghersi-Egea, Nathalie Strazielle
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Acta Neuropathologica Communications
Subjects:
Blood-brain barriers
Perinatal injury
Toll-like receptor
Innate immune system
Neuroinflammation
Neuroprotection
Online Access:https://doi.org/10.1186/s40478-019-0877-1

Internet

https://doi.org/10.1186/s40478-019-0877-1

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