Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target.

Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target.

Reverse transcription is the central defining feature of HIV-1 replication. We previously reported that the cellular eukaryotic elongation factor 1 (eEF1) complex associates with the HIV-1 reverse transcription complex (RTC) and the association is important for late steps of reverse transcription. H...

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Bibliographic Details
Main Authors: Dongsheng Li, Ting Wei, Daniel J Rawle, Fangyun Qin, Rui Wang, Dinesh C Soares, Hongping Jin, Haran Sivakumaran, Min-Hsuan Lin, Kirsten Spann, Catherine M Abbott, David Harrich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005289

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https://doi.org/10.1371/journal.ppat.1005289

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