T Cells Control Chemokine Secretion by Keratinocytes

T Cells Control Chemokine Secretion by Keratinocytes

The massive infiltration of lymphocytes into the skin is a hallmark of numerous human skin disorders. By co-culturing murine keratinocytes with splenic T cells we demonstrate here that T cells affect and control the synthesis and secretion of chemokines by keratinocytes. While pre-activated CD8+T ce...

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Bibliographic Details
Main Authors: Tabea Rauschenberger, Viola Schmitt, Muhammad Azeem, Stefan Klein-Hessling, Krisna Murti, Franziska Grän, Matthias Goebeler, Andreas Kerstan, Matthias Klein, Tobias Bopp, Edgar Serfling, Khalid Muhammad
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
chemokine
keratinocytes
IFN
lichen planus
T cells
Nfatc1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01917/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01917/full

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