Evaluation of Azathioprine-Induced Cytotoxicity in an In Vitro Rat Hepatocyte System

Azathioprine (AZA) is widely used in clinical practice for preventing graft rejection in organ transplantations and various autoimmune and dermatological diseases with documented unpredictable hepatotoxicity. The potential molecular cytotoxic mechanisms of AZA towards isolated rat hepatocytes were i...

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Bibliographic Details
Main Authors: Abdullah Al Maruf, Luke Wan, Peter J. O’Brien
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/379748