Similar NF-κB gene signatures in TNF-α treated human endothelial cells and breast tumor biopsies.

<h4>Background</h4>Endothelial dysfunction has been implicated in the pathogenesis of diverse pathologies ranging from vascular and immune diseases to cancer. TNF-α is one of the mediators of endothelial dysfunction through the activation of transcription factors, including NF-κB. While...

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Bibliographic Details
Main Authors: Martine Perrot-Applanat, Sophie Vacher, Aurore Toullec, Irma Pelaez, Guillaume Velasco, Françoise Cormier, Hanan El Sheikh Saad, Rosette Lidereau, Véronique Baud, Ivan Bièche
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21754991/pdf/?tool=EBI