Mitochondrial Transcription Factors TFA, TFB1 and TFB2: A Search for DNA Variants/Haplotypes and the Risk of Cardiac Hypertrophy

Mitochondrial Transcription Factors TFA, TFB1 and TFB2: A Search for DNA Variants/Haplotypes and the Risk of Cardiac Hypertrophy

Mitochondrial transcription factors mtTFA, mtTFB1 and mtTFB2 are required for the replication of mitochondrial DNA (mtDNA), regulating the number of mtDNA copies. Mice with a mtTFA deletion showed a reduced number of mtDNA copies, a reduction in respiratory chain activity, and a characteristic dilat...

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Main Authors: Cristina Alonso-Montes, Mónica G. Castro, Julián R. Reguero, Andreas Perrot, Cemil Özcelik, Christian Geier, Maximilian G. Posch, César Morís, Victoria Alvarez, Marta Ruiz-Ortega, Eliecer Coto
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2008/575323

Internet

http://dx.doi.org/10.1155/2008/575323

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