In vivo coupling of tau pathology and cortical thinning in Alzheimer's disease

In vivo coupling of tau pathology and cortical thinning in Alzheimer's disease

Abstract Introduction The deposition of neurofibrillary tangles in neurodegenerative disorders is associated with neuronal loss on autopsy; however, their in vivo associations with atrophy across the continuum of Alzheimer's disease (AD) remain unclear. Methods We estimated cortical thickness,...

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Bibliographic Details
Main Authors: Elijah Mak, Richard A.I. Bethlehem, Rafael Romero‐Garcia, Simon Cervenka, Timothy Rittman, Silvy Gabel, Ajenthan Surendranathan, Richard W. Bevan‐Jones, Luca Passamonti, Patricia Vázquez Rodríguez, Li Su, Robert Arnold, Guy B. Williams, Young T. Hong, Tim D. Fryer, Franklin I. Aigbirhio, James B. Rowe, John T. O'Brien
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Alzheimer's disease
Tau
Amyloid
Positron emission tomography
Atrophy
Cortical thickness
Online Access:https://doi.org/10.1016/j.dadm.2018.08.005

Internet

https://doi.org/10.1016/j.dadm.2018.08.005

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