LINGO-1 and AMIGO3, potential therapeutic targets for neurological and dysmyelinating disorders?

Leucine rich repeat proteins have gained considerable interest as therapeutic targets due to their expression and biological activity within the central nervous system. LINGO-1 has received particular attention since it inhibits axonal regeneration after spinal cord injury in a RhoA dependent manner...

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Bibliographic Details
Main Authors: Simon Foale, Martin Berry, Ann Logan, Daniel Fulton, Zubair Ahmed
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Neural Regeneration Research
Subjects:
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=8;spage=1247;epage=1251;aulast=Foale