Accumulation of alpha-synuclein within the liver, potential role in the clearance of brain pathology associated with Parkinson’s disease

Accumulation of alpha-synuclein within the liver, potential role in the clearance of brain pathology associated with Parkinson’s disease

Abstract Alpha-synuclein (α-syn) aggregation is the hallmark pathological lesion in brains of patients with Parkinson’s disease (PD) and related neurological disorders characterized as synucleinopathies. Accumulating evidence now indicates that α-syn deposition is also present within the gut and oth...

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Main Authors: Juan F. Reyes, Sara Ekmark-Léwen, Marina Perdiki, Therése Klingstedt, Alana Hoffmann, Emilia Wiechec, Per Nilsson, K. Peter R. Nilsson, Irina Alafuzoff, Martin Ingelsson, Martin Hallbeck
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Acta Neuropathologica Communications
Online Access:https://doi.org/10.1186/s40478-021-01136-3

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https://doi.org/10.1186/s40478-021-01136-3

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