Plant-Derived MINA-05 Inhibits Human Prostate Cancer Proliferation In Vitro and Lymph Node Spread In Vivo

Plant-Derived MINA-05 Inhibits Human Prostate Cancer Proliferation In Vitro and Lymph Node Spread In Vivo

Few treatment options exist for metastatic prostate cancer (PC) that becomes hormone refractory (HRPC). In vitro, plant-derived MINA-05 caused dose-dependent decreases in cell numbers in HRPC cell lines LNCaPC4-2B and PC-3, and in androgen-sensitive LNCaP-FGC, DuCaP, and LAPC-4, by WST-1 assay. MIN...

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Bibliographic Details
Main Authors: Kate Vandyke, Melanie Y. White, Terry Nguyen-Khuong, Kim Ow, Sharon C.-W. Luk, Elizabeth A. Kingsley, Alexandra Rowe, Shiu-Fun Pang, Bradley J. Walsh, Pamela J. Russell
Format: Article
Language:English
Published: Elsevier 2007-04-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Prostate cancer
G2M block
MINA-05 herbal treatment
lymph node metastases
clonogenic assays
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558607801023

Internet

http://www.sciencedirect.com/science/article/pii/S1476558607801023

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