Plant-Derived MINA-05 Inhibits Human Prostate Cancer Proliferation In Vitro and Lymph Node Spread In Vivo
Few treatment options exist for metastatic prostate cancer (PC) that becomes hormone refractory (HRPC). In vitro, plant-derived MINA-05 caused dose-dependent decreases in cell numbers in HRPC cell lines LNCaPC4-2B and PC-3, and in androgen-sensitive LNCaP-FGC, DuCaP, and LAPC-4, by WST-1 assay. MIN...
Main Authors: | Kate Vandyke, Melanie Y. White, Terry Nguyen-Khuong, Kim Ow, Sharon C.-W. Luk, Elizabeth A. Kingsley, Alexandra Rowe, Shiu-Fun Pang, Bradley J. Walsh, Pamela J. Russell |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2007-04-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558607801023 |
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