α-synuclein induced synapse damage is enhanced by amyloid-β<sub>1-42</sub>

<p>Abstract</p> <p>Background</p> <p>The pathogenesis of Parkinson's disease (PD) and dementia with Lewy bodies (DLB) is associated with the accumulation of aggregated forms of the α-synuclein (αSN) protein. An early event in the neuropathology of PD and DLB is the...

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Bibliographic Details
Main Authors: Williams Alun, Gentleman Steve, Bate Clive
Format: Article
Language:English
Published: BMC 2010-12-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/5/1/55