Insulin inhibits inflammation-induced cone death in retinal detachment

Insulin inhibits inflammation-induced cone death in retinal detachment

Abstract Background Rhegmatogenous retinal detachment (RD) involving the macula is a major cause of visual impairment despite high surgical success rate, mainly because of cone death. RD causes the infiltration of activated immune cells, but it is not clear whether and how infiltrating inflammatory...

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Bibliographic Details
Main Authors: Jean-Baptiste Conart, Guillaume Blot, Sébastien Augustin, Géraldine Millet-Puel, Christophe Roubeix, Fanny Beguier, Hugo Charles-Messance, Sara Touhami, José-Alain Sahel, Jean-Paul Berrod, Thierry Léveillard, Xavier Guillonneau, Cécile Delarasse, Florian Sennlaub
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Journal of Neuroinflammation
Subjects:
Retinal detachment
Cone degeneration
Inflammation
Mononuclear phagocytes
Insulin signaling
Online Access:https://doi.org/10.1186/s12974-020-02039-1

Internet

https://doi.org/10.1186/s12974-020-02039-1

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