A Cdc42-mediated supracellular network drives polarized forces and Drosophila egg chamber extension

During development, organs undergo large scale forces driven by the cytoskeleton but the precise molecular regulation of cytoskeletal networks remains unclear. Here, the authors report a Cdc42-dependent supracellular cytoskeletal network integrates local actomyosin contraction at tissue scale and dr...

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Bibliographic Details
Main Authors: Anna Popkova, Orrin J. Stone, Lin Chen, Xiang Qin, Chang Liu, Jiaying Liu, Karine Belguise, Denise J. Montell, Klaus M. Hahn, Matteo Rauzi, Xiaobo Wang
Format: Article
Language:English
Published: Nature Publishing Group 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15593-2