Restriction Enzyme Analysis of DNA Methylation in “Condensed” Chromatin of Ha-Ras-Transformed NIH 3T3 Cells

Increased amounts of chromatin condensation (i.e., localized areas of high DNA density, or chromatin higher order packing state) have been described in NIH 3T3 cells transformed with the Ha‐ras oncogene. The structural basis for this oncogene‐mediated alteration in nuclear organization is unknown. S...

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Bibliographic Details
Main Authors: Maria Luiza S. Mello, Ann F. Chambers, Benedicto C. Vidal, Wolfgang Planding, Ulrich Schenck
Format: Article
Language:English
Published: Hindawi Limited 2000-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/2000/138230