A novel mutual information-based Boolean network inference method from time-series gene expression data.

BACKGROUND:Inferring a gene regulatory network from time-series gene expression data in systems biology is a challenging problem. Many methods have been suggested, most of which have a scalability limitation due to the combinatorial cost of searching a regulatory set of genes. In addition, they have...

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Bibliographic Details
Main Authors: Shohag Barman, Yung-Keun Kwon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5298315?pdf=render