Mutation allele frequency threshold does not affect prognostic analysis using next-generation sequencing in oral squamous cell carcinoma

Mutation allele frequency threshold does not affect prognostic analysis using next-generation sequencing in oral squamous cell carcinoma

Abstract Background With the development of sequencing technologies, there may be some disputes on sequencing analysis. The aim of this study was to investigate different allele frequency thresholds of mutations in targeted genes on prognostic analyses using a panel of cancer associated gene exons (...

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Bibliographic Details
Main Authors: Jie Ma, Yong Fu, Yao-yao Tu, Ying Liu, Yi-ran Tan, Wu-tong Ju, Curtis R. Pickering, Jeffrey N. Myers, Zhi-yuan Zhang, Lai-ping Zhong
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Cancer
Subjects:
Oral squamous cell carcinoma
Next-generation sequencing
Mutation allele frequency
Online Access:http://link.springer.com/article/10.1186/s12885-018-4481-8

Internet

http://link.springer.com/article/10.1186/s12885-018-4481-8

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