Hsa-miR-125b Therapeutic Role in Colon Cancer Is Dependent on the Mutation Status of the TP53 Gene

Hsa-miR-125b Therapeutic Role in Colon Cancer Is Dependent on the Mutation Status of the TP53 Gene

Colon cancer is the third most common cancer type worldwide and is highly dependent on DNA mutations that progressively appear and accumulate in the normal colon epithelium. Mutations in the <i>TP53</i> gene appear in approximately half of these patients and have significant implications...

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Bibliographic Details
Main Authors: Diana Cenariu, Alina-Andreea Zimta, Raluca Munteanu, Anca Onaciu, Cristian Silviu Moldovan, Ancuta Jurj, Lajos Raduly, Alin Moldovan, Adrian Florea, Liviuta Budisan, Laura Ancuta Pop, Lorand Magdo, Mihai Tudor Albu, Rares Bogdan Tonea, Mihai-Stefan Muresan, Calin Ionescu, Bogdan Petrut, Rares Buiga, Alexandru Irimie, Diana Gulei, Ioana Berindan-Neagoe
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceutics
Subjects:
colon cancer
colorectal cancer
miR-125b
therapy
<i>TP53</i>
mutation
Online Access:https://www.mdpi.com/1999-4923/13/5/664

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https://www.mdpi.com/1999-4923/13/5/664

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