Genetic Modification of <i>mfsT</i> Gene<i> </i>Stimulating the Putative Penicillin Production in<i> Monascus ruber </i>M7 and Exhibiting the Sensitivity towards Precursor Amino Acids of Penicillin Pathway

Genetic Modification of <i>mfsT</i> Gene<i> </i>Stimulating the Putative Penicillin Production in<i> Monascus ruber </i>M7 and Exhibiting the Sensitivity towards Precursor Amino Acids of Penicillin Pathway

<b>: </b>The biosynthesis of penicillin G (PG) is compartmentalized, which forces penicillin and its intermediates to cross the membrane barriers. Although many aspects around the penicillin intermediates traffic system remain unclosed, the transmembrane transporter protein involvement h...

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Bibliographic Details
Main Authors: Rabia Ramzan, Muhammad Safiullah Virk, Zafarullah Muhammad, Amani Mohedein Mohammed Ahmed, Xi Yuan, Fusheng Chen
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Microorganisms
Subjects:
Monascus ruber M7
edible fungi
β-lactam
penicillin G
isopenicllin N
secondary metabolites
major facilitator superfamily transporter
phenylacetic acid
D-valine
L-cysteine
Online Access:https://www.mdpi.com/2076-2607/7/10/390

Internet

https://www.mdpi.com/2076-2607/7/10/390

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