Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy

Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy

Epigenetic regulations of autophagy have emerged as mechanisms for maintaining cellular homeostasis. Here the authors reveal that the CARM1-Pontin-FOXO3a signaling axis can activate autophagy related genes through enhancer activation.

Bibliographic Details
Main Authors: Young Suk Yu, Hijai R. Shin, Dongha Kim, Seon Ah Baek, Seon Ah Choi, Hyejin Ahn, Amen Shamim, Jeonghwan Kim, Ik Soo Kim, Kyeong Kyu Kim, Kyoung-Jae Won, Sung Hee Baek
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20080-9

Internet

https://doi.org/10.1038/s41467-020-20080-9

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