Protective Effects of a Discontinuous Treatment with Alpha-Lipoic Acid in Obesity-Related Heart Failure with Preserved Ejection Fraction, in Rats

Protective Effects of a Discontinuous Treatment with Alpha-Lipoic Acid in Obesity-Related Heart Failure with Preserved Ejection Fraction, in Rats

Obesity induces hemodynamic and humoral changes that are associated with functional and structural cardiac remodeling, which ultimately result in the development of heart failure (HF) with preserved ejection fraction (HFpEF). In recent years, pharmacological studies in patients with HFpEF were mostl...

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Bibliographic Details
Main Authors: Cristina Pop, Maria-Georgia Ștefan, Dana-Maria Muntean, Laurențiu Stoicescu, Adrian Florin Gal, Béla Kiss, Claudiu Morgovan, Felicia Loghin, Luc Rochette, Benjamin Lauzier, Cristina Mogoșan, Steliana Ghibu
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Antioxidants
Subjects:
heart failure with preserved ejection fraction
obesity
oxidative stress
antioxidants
alpha-lipoic acid
Online Access:https://www.mdpi.com/2076-3921/9/11/1073

Internet

https://www.mdpi.com/2076-3921/9/11/1073

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