Mutation profiling in eight cases of vagal paragangliomas

Mutation profiling in eight cases of vagal paragangliomas

Abstract Background Vagal paragangliomas (VPGLs) belong to a group of rare head and neck neuroendocrine tumors. VPGLs arise from the vagus nerve and are less common than carotid paragangliomas. Both diagnostics and therapy of the tumors raise significant challenges. Besides, the genetic and molecula...

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Main Authors: Anna V. Kudryavtseva, Dmitry V. Kalinin, Vladislav S. Pavlov, Maria V. Savvateeva, Maria S. Fedorova, Elena A. Pudova, Anastasiya A. Kobelyatskaya, Alexander L. Golovyuk, Zulfiya G. Guvatova, George S. Razmakhaev, Tatiana B. Demidova, Sergey A. Simanovsky, Elena N. Slavnova, Andrey А. Poloznikov, Andrey P. Polyakov, Nataliya V. Melnikova, Alexey A. Dmitriev, George S. Krasnov, Anastasiya V. Snezhkina
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Medical Genomics
Subjects:
Vagal paraganglioma
Pathogenic/likely pathogenic mutations
SDHx genes
SHD assembly factor-coding genes
Exome
High-throughput sequencing
Online Access:http://link.springer.com/article/10.1186/s12920-020-00763-4

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http://link.springer.com/article/10.1186/s12920-020-00763-4

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